Kamis, 29 Desember 2011

[L208.Ebook] Download PDF Nemesis: One Man and the Battle for Rio, by Misha Glenny

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Nemesis: One Man and the Battle for Rio, by Misha Glenny

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Nemesis: One Man and the Battle for Rio, by Misha Glenny

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Nemesis: One Man and the Battle for Rio, by Misha Glenny

The astonishing story of an ordinary man forced to make a decision that would turn his world upside down
 
How did Antônio Francisco Bonfim Lopes, a hardworking young father, become the king of Rocinha, the largest slum in Rio; the head of a drug cartel; and perhaps Brazil’s most wanted criminal, known to all as “Nem”? Nemesis is the riveting account of his ruthless ascent in Rio’s terrifying underworld, his sway over its anarchic outlaw culture, and his accidental fall. Nem tried to bring welfare and justice to a playground of gang culture and destitution, but he quickly found himself embroiled in a world of gold hunters and evangelical pastors, bent police officers and rich-kid addicts, quixotic politicians and drug lords with math degrees.

Spanning rainforests and high-security prisons, filthy slums and glittering shopping malls, Nemesis chronicles Brazil’s journey into the global spotlight—and the battle for the beautiful but damned city of Rio as it struggles to break free from a tangled web of corruption, violence, drugs and poverty. Nem is held at the center of it all, locked in a fight for his country’s future.


From the Hardcover edition.

  • Sales Rank: #145873 in eBooks
  • Published on: 2016-02-09
  • Released on: 2016-02-09
  • Format: Kindle eBook

Review
“Fearlessly reported with impressive detail….Mr. Glenny doesn’t preach or moralize. He shows that law enforcement in Rio is as problematic as the criminals, and in doing so, he paints what seems to be a true picture. This is a balanced book in the best sense.”

“Incredible…. an epic, painstakingly detailed story about the rise of a favela kid to king of an empire…. what Glenny does so well is explain the context for Rio’s drug world, and the battle to contain and (to use the word local officials concerned about Rio’s global image employ) “pacify” it. What emerges is not just a study of one man and how he came to control a cartel, but a portrait of a city bursting with new arrivals from poorer parts of Brazil, unfortunates who wind up clustered in shantytowns that lack adequate water, electricity and, crucially, economic opportunity…. Without glorifying Nem or trying too hard to justify his bitterly violent enterprise, Glenny humanizes a kind of person we tend to see drawn as a two-dimensional character. And he shows how the fortunes of Rio ― to say nothing of its reputation on the world stage ― are tied to its ability to do well by its poorest and most marginalized citizens.”

“A balanced, but ultimately sympathetic, biography of the leader of a relatively small local drug cartel. Nem’s personal story anchors more profound reportage about Brazil’s parallel economic and political systems―specifically, Rocinha’s existence as a largely autonomous urban community and what happens when the government attempts to destroy, substantially reduce, or otherwise encroach on that autonomy.”

“His name is Antônio Francisco Bonfim Lopes. But you can call him Nemesis, everyone else does, and he was the don of Rocinha, the largest of Rio’s slums, known as favelas. He is also the protagonist of Misha Glenny’s fine book, the grim, elucidating Nemesis: One Man and the Battle for Rio…. For all the tale’s vileness, it is very skillfully told and a very strong piece of journalism.”

“In 1999, with no criminal background, Antonio Francisco Bonfim Lopes was a typical resident of Rocinha, trying to figure out how to survive and support his family in one of Rio de Janeiro’s largest favelas. Less than six years later he was known as Nem, in charge of the large criminal organization unofficially ruling over Rocinha. The story of Nem acts as the glue for this title, in which journalist Glenny successfully explores the history of Rio de Janeiro, focusing on the violence, drug trade, politics, police forces, and related corruption within Rio’s favelas since the 1960s….Glenny employs a writing style that both keeps the story moving and the reader wanting more.”

About the Author
Misha Glenny is the author of Dark Markek McMafia, The Rebirth of History, The Fall of Yugoslavia (which won the Overseas Press Club Award in 1993 for Best Book on Foreign Affairs), and The Balkans: Nationalism, War and the Great Power, 1804-1999. He was a BBC Central Europe correspondent-he covered the fall of Communism and the wars in the former Yugoslavia-and has been regularly consulted by the U.S. and European governments on major policy issues.

Zach began pursuing the creative life early on in his mother's dance studio. He upped his artistic ante by transfering to Interlochen Arts Academy where he began to study acting. Zach Villa has acquired considerable acclaim as an actor, musician, vocalist, dancer & songwriter. A 'jack of all trades,' Zach appeared on Broadway and at Carnegie Hall before re-locating to the West coast

Most helpful customer reviews

4 of 4 people found the following review helpful.
Even better than McMafia
By Jack R. Selby
A true tour-de-force, even better than McMafia. An amazing primer on the rise of favela culture, humanized by the portrayal of one of its most notorious Don's. Unravels the socio-economic complexities in Rio while also revealing the dysfunction of Rio law enforcement. A true "page-turner" despite the over use of the phrase and couldn't recommend it more highly. Bravo!

3 of 3 people found the following review helpful.
Terrific!
By sandrine
I picked up this book from the library on a whim and couldn't put it down! It is extremely well written and researched making you feel as if you are actually in the midst of the story. It answered a lot of questions that I always had about Rio de Janeiro, and more specifically the culture and politics of the infamous favelas as well as the country at large. This isn't a story about a sociopathic criminal, rather it details instead how an ordinary, decent, hardworking initially law abiding human being who was simply trying to play the cards he was dealt, found himself drawn into the vortex of crime through sheer (and very sad) desperation. With the 2016 summer Olympic Games fast approaching, this book makes for an especially compelling read. It is a tragic, haunting and exciting story that will keep you turning each page long into the night.

0 of 0 people found the following review helpful.
Rio, crime bosses -- great adventures -- marvelous stories
By Robert C Ross
Read at the New York Society Library.

This is a fascinating story, well told but for some over the top sections that could have benefitted from some more careful editing.

The "hero" owned a vast section of Rio, and there are many echoes of the Godfather in Mario Puzo's The Godfather . Francisco Bonfim Lopes is just an ordinary guy who understands how to get ahead in a very complex world. Crime, of course, but he fills a very important governmental function in a part of Rio where the formal government does not function, some times at all, often badly, and almost never well.

It is fascinating to read about all of the various activities he engaged in, and to marvel really that Glenny was able to earn Lopes' confidence enough to see this rise to power from the inside.

If you have any interest in the fascinating history of Rio or Brazil, or in crime bosses wherever located, you will enjoy the story and make allowances for the writing.

Robert C. Ross
April 2016

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Minggu, 25 Desember 2011

[B693.Ebook] Free PDF The Introvert's Way: Living a Quiet Life in a Noisy World (Perigee Book), by Sophia Dembling

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The Introvert's Way: Living a Quiet Life in a Noisy World (Perigee Book), by Sophia Dembling

For anyone who loved Susan Cain’s Quiet, comes this practical manifesto sharing the joys of introversion…

This clever and pithy book challenges introverts to take ownership of their personalities...with quiet strength. Sophia Dembling asserts that the introvert’s lifestyle is not “wrong” or lacking, as society or extroverts would have us believe. Through a combination of personal insights and psychology, The Introvert’s Way helps and encourages introverts to embrace their nature, to respect traits they may have been ashamed of and reframe them as assets.

You’re not shy; rather, you appreciate the joys of quiet. You’re not antisocial; instead, you enjoy recharging through time alone. You’re not unfriendly, but you do find more meaning in one-on-one connections than large gatherings.

By honoring what makes them unique, this astute and inspiring book challenges introverts to “own” their introversion, igniting a quiet revolution that will change how they see themselves and how they engage with the world.

  • Sales Rank: #45342 in Books
  • Brand: Brand: Perigee Trade
  • Published on: 2012-12-04
  • Released on: 2012-12-04
  • Original language: English
  • Number of items: 1
  • Dimensions: 7.47" h x .53" w x 5.39" l, .35 pounds
  • Binding: Paperback
  • 208 pages
Features
  • Used Book in Good Condition

Review
“In this thought-provoking treatise on the quieter types, Dembling, the blogger behind Psychology Today’s “The Introvert’s Corner,” proposes a wholesale rethinking of what it means to be an introvert…. Dembling’s account is refreshingly candid and straightforward—“I am an introvert,” she writes, “And there’s not a damn thing wrong with me.”
-Publishers Weekly
 
“Unlike Quiet, it not only provides scientific and cultural background but also practical tips and a thorough-note of complete understanding of the introvert’s nature. An introvert myself, I have never read a book that I have so truly felt myself in.” 
-Psych Central
 
“Dembling urges introverts to embrace their need for solitude, reflection, and regeneration with no apologies. It's what makes us who we are.”
-Cleveland Plain Dealer

About the Author
Sophia Dembling writes The Introvert’s Corner blog for Psychology Today. Her previous books include The Yankee Chick’s Survival Guide to Texas, and she has published hundreds of articles and essays in magazines, newspapers, and websites.

Most helpful customer reviews

143 of 147 people found the following review helpful.
Helpful & Insightful
By The Simply Luxurious Life
As a professed introvert, understanding the beauty of being someone who prefers quiet over chaos more often than not has become an interest of mine. And upon writing the post shared this past February about embracing one's introversion, I was pleasantly surprised to discover many fellow introverts.

Upon discovering Sophia Dembling's new book The Introvert's Way, I had the fortunate opportunity to review a copy before it became available (released today - Dec. 4th). While similar to Susan Cain's Quiet: The Power of Introverts in a World that Can't Stop Talking, Dembling book is quite validating (". . . introverts can perhaps lay claim to high levels of creativity"), but at the same time Dembling, herself an introvert, offers accessible advice on how to interact successfully and create quality relationships with others that may be far more extroverted than we understand.

With chapters titled: What Quiet Says, Introverts are Not Failed Extroverts, Loneliness is a State of Mind and Mistakes Introverts Make, it is authentic based on her own experiences, helpful with its relatable situations that you may have thought you were the only one experiencing and wise on how to deal with those who may not understand. After all, it's okay if you enjoy your own company more often than not (in fact, it's a very good thing), and once you understand that this idea that extroversion is better and the American way is all a myth, you too will hopefully breathe a sigh of relief and go about accepting yourself for exactly who you are, being comfortable living in a way that works for you. Needless to say, I highly recommend this book.

109 of 116 people found the following review helpful.
Way To Be an Introvert
By Deb
The Table of Contents is what sold me on this book. In and off itself, it captures the challenges, quirks, and perks of being an introvert:
* Introverts Unite
* What Would Jung Say?
* The Great American Racket
* Science Says We're Not Necessarily Shy
* Born to Be Mild
* Quiet Riot
* Just Intense Enough
* The Slow Train of Thought
* The Internal Flame
* What Quiet Says
* The Fertile Void
* I Like to Watch
* Energy In, Energy Out
* "We Didn't Know You Were an Introvert, We Just Thought You Were a Bitch."
* Magic Words to Plug Energy Drains
* Introverts Are Not Failed Extroverts
* I Like People...Just Not All People All the Time
* Don't Call Us, We'll Call...Well, No, Maybe We Won't
* We Gotta Fight for Our Right Not to Party
* Loneliness Is a State of Mind
* The Happiness Bias
* Who's a Narcissist?
* Turning the Extrovert Advantage Upside Down
* The Party Predicament
* The Bathroom and Other Party Survival Skills
* Hell Is a Cocktail Party
* Fact 1: Some People Are Boring, Fact 2: You Are Not Obligated to Listen to Them
* Saying Yes When You Want to Say No (and Vice Versa)
* Extroversion in a Bottle
* There Must Be Fifty Ways to Leave a Party
* Life Through Introvert Eyes
* "It'll Be Fun!" They Say, But We Beg to Differ
* Fun, Introvert Style
* Friend, "Friends," Acquaintances, and Why Bother?
* The Online Extrovert
* The Happy Noise of Extroversion
* Because They Love You
* Itty-Bitty Introverts
* Love Us, but Leave Us Alone (Sometimes)
* I F#&$ing Hate It When They Say That
* A Team of One
* Introvert Feats of Derring-Do
* First, Leave the House and Other Tips for Making Friends
* Mind Fullness to Mindfulness
* Mistakes Introverts Make
* Affirmations for Introverts
* Middle Ground
* C'mon People Now, Smile on Your Brother

Not surprisingly, the rest of the book is just as insightful, witty, and engaging. In addition to exploring, explaining, and validating the introvert's way (which really is way cool once you can fully appreciate it), it helps introverts "calibrate our need for solitude with our need for human interaction." (p. 70) And, to that end, the author offers some great affirmations (pp. 177-179):
*Staying home is doing something.
*My presence is a gift, not a requirement.
*I like who I like.
*Listening to bores is not my job.
*Managing my energy is a favor to myself and everyone around me.
*Saying no can be a kindness.
*I can love other people and still not be responsible for their good time.
*Just because I'm quiet doesn't mean I have nothing to say.
*Putting on my dog and pony show is optional.
*A ringing phone is not a mandate.
*I know what I need better than anyone else.
*Other people's desire for me to participate is not more important than my desire not to participate.

If you're an introvert, you'll likely feel understood, inspired, and deeply entertained by this book. The book's a breeze to read through--the only challenge might be finding a quiet spot in the noisy world where you can soak it all in. (And, of course, there's no need to answer any phones while doing so.)

69 of 73 people found the following review helpful.
Inside the mind of an introvert
By Zachary Goldman
I was introduced to this book after reading an article by Sophia Dembling in the Wall Street Journal on December 14, 2012 entitled "All I Want for Christmas Is...A Little Space," so I picked up a copy of "The Introvert's Way" in hopes of learning more about introverts like myself. I was not disappointed.

Ms. Dembling immediately dives into shattering the common misconceptions on introverts. Distinguishing shyness from introversion, she states "shy people are scared of socializing. Introverts just aren't always interested in it." She separates introverts into "shy" and "not shy" categories, shredding the common misconception of all introverts being the former. Because of society's preference for extroversion over introversion, a lot of the "not shy" introverts are able to give off the impression of being an extrovert when they really aren't. Ms. Dembling even cites a study that shows it's a lot easier for introverts to act as extroverts than it is for extroverts to act as introverts, perhaps because introverts are more experienced at putting on--as Ms. Dembling refers to it--the "dog-and-pony show."

Moving beyond the comparisons between extroverts and introverts, this book does teach a lot to introverts about their own nature. She spends a bit of time talking about what introverts like to do, such as hiking, biking, kayaking, coffee shops, reading, walking, yoga, one-on-one conversations with good friends, writing, and other activities that encourage concentration and solitude. I'm personally interested in trying out her suggestion on mountain climbing, so perhaps other readers will be encouraged to try some of the other suggestions that Ms. Dembling says introverts like to do.

Most of all, as a self-proclaimed introvert, I was already comfortable with my own nature. However, Ms. Dembling's book made me even more content with myself. She writes that extroverts and introverts are better off letting each other be themselves, since we won't be able to change each others' nature anyway (introversion will probably stick with you throughout your entire life, she writes in the aforementioned Wall Street Journal article). Since nobody can change an introvert's way, we may as well try to understand it. This book is a good place to start.

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Sabtu, 24 Desember 2011

[R323.Ebook] Fee Download The African Background Outlined Or Handbook for the Study of the Negro, by Carter G. Woodson

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The African Background Outlined Or Handbook for the Study of the Negro, by Carter G. Woodson

  • Sales Rank: #10995511 in Books
  • Published on: 1969
  • Binding: Paperback
  • 478 pages

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Jumat, 23 Desember 2011

[U590.Ebook] Download PDF Laboratory Manual and Workbook for Biological Anthropology: Engaging with Human Evolution, by K. Elizabeth Soluri, Sabrina C. Agarwal

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Laboratory Manual and Workbook for Biological Anthropology: Engaging with Human Evolution, by K. Elizabeth Soluri, Sabrina C. Agarwal

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A vividly illustrated, flexible, and topically balanced manual with a critical-thinking approach―all at an unbeatable value.

  • Sales Rank: #146472 in Books
  • Published on: 2015-07-01
  • Original language: English
  • Number of items: 1
  • Dimensions: 10.90" h x 1.00" w x 9.30" l, .0 pounds
  • Binding: Spiral-bound
  • 450 pages

About the Author
K. Elizabeth Soluri received her B.A. from New York University and her M.A. and Ph.D. from the University of California, Berkeley. She has conducted anthropological field and laboratory research across the United States, including work in Valley Forge National Historical Park, Hawaii, and the central California coast. Elizabeth is especially interested in pedagogy and issues of student learning, and her dissertation research focused on redesigning, implementing, and evaluating effective teaching methods for undergraduate anthropology courses, particularly biological anthropology. Elizabeth has taught anthropology courses at several 2-year and 4-year institutions throughout the San Francisco Bay area.

Sabrina C. Agarwal is an Associate Professor of Anthropology at the University of California, Berkeley. She received her B.A. and M.Sc. from the University of Toronto and her Ph.D. from the same institution, working in both the Department of Anthropology and the Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto. Her research interests are focused broadly upon the age, sex, and gender-related changes in bone quantity and quality, particularly the application of life course approaches to the study of bone maintenance and fragility and its application to dialogues of social identity and embodiment in bioarchaeology. She has authored several related scholarly articles and edited volumes, most recently the volume (with Bonnie Glencross) Social Bioarchaeology (Wiley-Blackwell). She is interested in the philosophies of teaching, and is actively involved in the pedagogical training of current and future college instructors.

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1 of 1 people found the following review helpful.
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By Gabriel
It's a book, It;s required for the course and paid for the new edition as I had no choice. Overpriced books just like the rest of them but it has all the information you need for the lab course.

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Senin, 05 Desember 2011

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Selasa, 15 November 2011

[E478.Ebook] Download Global Rules: America, Britain and a Disordered World, by James E. Cronin

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Global Rules: America, Britain and a Disordered World, by James E. Cronin

The Second World War created and the Cold War sustained a “special relationship” between America and Britain, and the terms on which that decades-long conflict ended would become the foundation of a new world order. In this penetrating analysis, a new history of recent global politics, author James Cronin explores the dramatic reconfiguring of western foreign policy that was necessitated by the interlinked crises of the 1970s and the resulting global shift toward open markets, a movement that was eagerly embraced and encouraged by the U.S./U.K. partnership.
 
Cronin’s bold revisionist argument questions long-perceived views of post–World War II America and its position in the world, especially after Vietnam. The author details the challenges the economic transition of the 1970s and 1980s engendered as the United States and Great Britain together actively pursued their shared ideal of an international assemblage of market-based democratic states. Cronin also addresses the crises that would sorely test the system in subsequent decades, from human rights violations and genocide in the Balkans and Africa to 9/11 and militant Islamism in the Middle East to the “Great Recession” of 2008.

  • Sales Rank: #1218712 in Books
  • Published on: 2014-10-28
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.50" h x 6.50" w x 1.50" l, .92 pounds
  • Binding: Hardcover
  • 416 pages

Review
'Despite everything, the contemporary world order remains Anglo-American - and it is likely to stay that way. In this major new book James Cronin shows why this is so, combining a mastery of historical detail with an understanding of how geopolitics and political economy shape world politics. It is an absorbing read.' – Andrew Gamble, author of The Spectre at the Feast: Capitalist Crisis and the Politics of Recession (Andrew Gamble)

'A perceptive analysis and account of one of the critical relationships in international relations. Elegantly written, thoroughly researched, and persuasively argued, this is an essential read for anyone interested in the dynamics of the Anglo-American relationship and more broadly the working of the international system.' - Erik Goldstein, author of The First World War’s Peace Settlements: International Relations, 1918–1925 (Erik Goldstein)

“A deeply researched and lucid history of the period between the Vietnam War and the present day.”?Foreign Affairs (Foreign Affairs)

“The thesis is solid, refreshing and holds water. It is an extremely competent work… While much of the material presented here is not new to specialists, it is, as far as I am aware, the first time it has been presented in as lucid and cogent manner as this.”—Tore T. Petersen, American Historical Review (Tore T. Petersen American Historical Review 2015-12-01)

About the Author
James Cronin is professor of history at Boston College and an affiliate of the Minda De Gunzburg Center for European Studies, Harvard University. He lives in Watertown and Wellfleet, MA.

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Minggu, 13 November 2011

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Blind Aphrodite, by Renee Bernard

Lady Claire Aylesbury is beautiful, strong-willed and blind. When her twin brother, Edward, mysteriously disappears in the revolution-torn American Colonies, she is forced to venture out to find him, desperate to escape a limited future and the threat of a loveless marriage. Captain Rutger Grayson has turned his back on the world, unable to accept the scars that fate has inflicted. The once dashing buccaneer struggles to shield his heart as Claire draws him into a world of intrigue and danger. He seeks only to protect her against cruel betrayal without surrendering his soul. Set in 1780, a twist on Beauty and the Beast like no other, this is a love story for the ages that proves that when love is blind, anything is possible. From USA Today Bestselling author, Renee Bernard, on the fifteenth anniversary of her first novel's appearance, she relaunches this timeless tale with new scenes and a fresh lift for readers to enjoy!

  • Sales Rank: #3331274 in Books
  • Published on: 2015-10-29
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.00" h x .29" w x 6.00" l, .40 pounds
  • Binding: Paperback
  • 116 pages

About the Author
Renee Bernard is a freelance writer for "Romantic Times Bookclub" magazine. "A Lady's Pleasure" is her first novel. She has also written a story, "Mischief's Holiday," for the anthology "The School for Heiresses". Renee lives in the Sierra Nevada Mountains in Northern California. Visit her website at ReneeBernardAuthor.com.

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4 of 4 people found the following review helpful.
An Entertaining Tale
By Regina Pounds
A sea captain, horribly scarred, and a beautiful damsel in distress, who is blind to his flaws, are destined to fall in love with one another. Together, they uncover the dastardly plot behind her brother's disappearance. Cast a wicked, depraved villain and his greedy, lusty female accomplice into the fray, and you have 'Blind Aphrodite' -- an entertaining tale. Some violence and graphic descriptions of the beautiful as of the ugly side of the act called 'love-making' make for adult reading. Certain plot twists give this historical romance a gothic touch. Ms Bernard shows, rather than tells. A fine debut for a talented writer.

1 of 1 people found the following review helpful.
Rerelease of Blind Aphrodite
By Barbara Rickett
I am fortunate to have read the original book and also the rerelease.This is a wonderful adaptation of beauty and the beast style.This is a historical romance .A blind heroine must find her brother who has gone across the ocean and she had not heard from him.She must find him and enlists the help of a ship's Captain.She gets to know him as a person on their voyage without being able to see his disfigurement. This is a true love story which is well worth reading. Renee takes us on an adventure as they discover each other.A great book by a fantastic author.

1 of 1 people found the following review helpful.
A Keeper!
By Jeannine Meador
This story was so special with a heroine who was like no other...she was real...not defined by her disability and allowed it not to control anything in her life. The story was fast paced and a book for staying up all night with! I loved it but was sad to come to the final page. We need more of this caliber of writing! This author goes to the top of my must read list and her books will remain in my library for re-reading!!

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  • Published on: 2015-10-17
  • Released on: 2015-10-17
  • Format: Kindle eBook

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  • Sales Rank: #169016 in Books
  • Published on: 2016-08-03
  • Original language: English
  • Number of items: 1
  • Dimensions: 10.75" h x 8.50" w x .75" l, 1.75 pounds
  • Binding: Paperback
  • 322 pages

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Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format.

Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases.

  • Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease
  • Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain
  • Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations

  • Sales Rank: #657608 in Books
  • Published on: 2014-11-27
  • Original language: English
  • Number of items: 1
  • Dimensions: 11.00" h x 2.20" w x 8.80" l, .0 pounds
  • Binding: Hardcover
  • 1464 pages

Review

"...a thoroughly updated, essential book on the genetics of neurological and psychiatric disorders. Every clinician and researcher in neurology and psychiatry ought to be aware of the important information contained in this outstanding book. Score: 91 - 4 Stars" --Doody's

"Genetics and genomics have changed the practice of neurology and will continue to have huge impact on every discipline of medicine. In this fifth edition of the "bible" of Neurogenetics, Dr. Rosenberg and Dr. Pascual have done a remarkable job in leading the assembly of a volume that is truly representative of this rapidly advancing field –more than ½ of the chapters are new since the last edition. Here, in one place, one can access not only the genetics of common disorders, but virtually every metabolic disorder seen by neurologists, and new chapters on some of the major psychiatric disorders where genetics has played a crucial role in beginning to clarify disease pathophysiology. All of the major disorders, from those afflicting cortex to peripheral muscle are covered by the leading experts in their fields in a clear and authoritative manner. The organization is well conceived and progressive, beginning by providing a conceptual basis for the field, covering basic topics such as genetic counseling, genotype-phenotype relationships, the determination of causality in genetics, and new technologies such as genome sequencing in an exceptionally clear and comprehensive manner. Whether an expert or novice, if you are looking for one book that covers the field from A to Z, this is it." --Daniel Geschwind, Gordon and Virginia MacDonald Distinguished Professor Neurology, Psychiatry and Human Genetics and Director, Center for Autism Research and Treatment, Semel Institute, University of California, Los Angeles, CA

From the Back Cover

Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format.

Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases.

About the Author
Roger N. Rosenberg, MD holds the Abe (Brunky), Morris and William Zale Distinguished Chair and Professor of Neurology, University of Texas Southwestern Medical Center at Dallas. He served as Chair of the Department of Neurology from 1973- 1991. He is the founding Director of the NIH funded Alzheimer’s Disease Center at UT Southwestern and it has been funded through five consecutive competitive funding cycles since 1988 and will be funded through 2016 representing 27 years of continuous NIH Center funding. He is certified by the American Board of Psychiatry and Neurology. He served as Chief Resident in Neurology to H. Houston Merritt, MD, Neurological Institute, Columbia University Medical Center, New York, 1967-1968. He was a Post-Doctoral Research Fellow for Marshall Nirenberg, PhD, Laboratory of Biochemical Genetics, National Institutes of Health, 1968-1970.
Dr. Rosenberg has received important honors and awards including the prestigious UT Chancellor’s Discovery Lecture, invited by Chancellor Francisco Cigarroa for the Chancellor’s Council Meeting and Symposium, the University of Texas System, 2013. The Discovery Lecture was: “DNA Aß42 Vaccination as Therapy for Alzheimer’s Disease”. He was awarded the World Federation of Neurology, 1st Science Medal for Scientific Achievements in Neurology and Neuroscience, presented at the World Congress of Neurology in Bangkok, Thailand in 2009.
He is an Honorary Member (Elected) of the American Neurological Association, 2006 and the American Academy of Neurology 1997.
He received the Nancy R. McCune Research Award of the Alzheimer’s Association (AWARE) (2005).
He was the Robert Wartenberg Lecturer of the American Academy of Neurology, 2000, and his lecture was “The Molecular and Genetic Basis of Alzheimer’s Disease”.
He is an elected Honorary Member, Spanish Neurological Society, 1994. He was awarded the 1st Distinguished Neurology Alumnus Award of the Neurological Institute; Columbia University Medical Center; 1994.
He has been the Editor in Chief, JAMA Neurology (1997- present) and a member of the Editorial Board of JAMA (1997-present).
He was elected a Fellow, American Association for the Advancement of Science, February 1991
He was elected President of the American Academy of Neurology (1991-1993) and
1st Vice President of the American Neurological Association (1988-89). He received the Northwestern University Medical School Alumni Association Merit Award (1986).
In 2006, he published for the first time that a DNA A ß42 vaccine administered with the gene gun method into the skin of Alzheimer disease model mice can reduce Aß42 peptide levels in the brain by 50% with anti-A ß42 antibody of the IgG1/Th2 type which is known to be anti-inflammatory. He received in 2009 a US Patent as Inventor of “Amyloid ß Gene Vaccines”. This DNA vaccine has the potential to be a safe and effective therapy to prevent Alzheimer disease.
He described Machado-Joseph disease (MJD), an autosomal dominant ataxia, with William Nyhan, M.D. Ph.D, in 1976, for the first time. MJD is now the most common autosomal domiant spinocerebellar ataxia world-wide.
Dr. Rosenberg has published over 270 original scientific papers, chapters, reviews and editorials. He is the founding editor and senior editor since 1993 for all five editions of “The Molecular and Genetic Basis of Neurological and Psychiatric Diseases”.

Juan M. Pascual is the inaugural holder of The Once Upon a Time Foundation Professorship in Pediatric Neurologic Diseases. He is a tenured faculty member in the Departments of Neurology and Neurotherapeutics, Physiology and Pediatrics and in the Eugene McDermott Center for Human Growth & Development / Center for Human Genetics and is Director of the Rare Brain Disorders Program (Clinic and Laboratory). He is also a member of the Division of Pediatric Neurology, of the graduate Ph.D. programs in Neuroscience and Integrative Biology, and of the postgraduate clinical training programs in Neurology, Pediatric Neurology, Pediatrics and Medical Genetics. He also teaches at the UT Southwestern Medical School. Dr. Pascual directs a highly collaborative research laboratory and is credentialed at Children's Medical Center Dallas, UT Southwestern University Hospitals and Clinics and Parkland Memorial Hospital, where he consults on inpatients and outpatients with particularly complex or severe diseases. Much of his research is funded by the National Institutes of Health. He received certification in Neurology with Special Qualification in Child Neurology from the American Board of Psychiatry and Neurology. As one of few actively practicing pediatric neurologists in the U.S. who is also a laboratory scientist, Dr. Pascual is interested in the molecular mechanisms that cause inherited metabolic and excitability disorders using electrophysiology and nuclear magnetic resonance both in human subjects and in models of human diseases. His laboratory is located in the newest biomedical research building at UT Southwestern and is an integral part of the Department of Neurology and Neurotherapeutics. The laboratory is home to scientists from very broad backgrounds and levels of training and expertise who have joined efforts to endow both pediatric neurology and human developmental neuroscience with a strong scientific basis. As a clinician, Dr. Pascual specializes in genetic and metabolic diseases of the nervous and neuromuscular systems of infants, children and adults with a particular emphasis on complex diagnostic problems, second opinions for patients visiting from the rest of the U.S. and abroad, and in clinical trials. Dr. Pascual has special clinical research expertise in rare diseases, glucose metabolism, mitochondrial, degenerative, and multi-organ disorders. Dr. Pascual has co-authored over two dozen scientific, medical and philosophical textbooks. He is the editor, together with Dr. Roger Rosenberg of Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease (5th edition, Academic Press, forthcoming). He is now writing a new textbook on Progressive and Degenerative Brain Disorders in Children.

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